Custom and Toll Manufacturing
Piedmont Chemical is a trusted provider of custom chemical toll manufacturing across the USA, with additional reach into Canada, Mexico, and global markets. With multi-site manufacturing capabilities in North Carolina, South Carolina, Tennessee, and Texas, we deliver customized solutions backed by technical expertise, flexibility, and a commitment to quality.
As a family-owned company with over 85 years in the industry, we partner closely with each customer to ensure the success of every project, from initial concept to full commercial scale.
Comprehensive Toll Manufacturing Capabilities
At Piedmont, our toll manufacturing services are designed around one goal: to help you bring your chemical innovation to market safely, efficiently, and cost-effectively. We specialize in custom chemical toll manufacturing and offer scalable solutions for specialty chemistries.
Core Capabilities Include:
- Lab-to-plant development
- Confidential process handling
- Small- to large-volume production
- Multi-reactor configurations
- Complex synthesis & formulation support
Our technical staff works as an extension of your team, offering expert guidance from early R&D through commercialization. Our Pilot Program supports small-batch testing and scale-up, allowing seamless transitions from validation to production.
Plant Production Capabilities
Our facilities are designed to accommodate a broad range of synthesis methods and batch sizes. We offer:
Glass Reactors
- 1,000 to 2,000 gallon sized sise reactors
- Steam and pressure control
- Reflux and distillation
- Straight columns
Stainless Steel Reactors
- 250 to 5,000 gallons
- Steam and pressure
- Hot-oil capability
- Reflux and distillation
- Variation of straight and packed columns
- Closed-loop Dimethyl Sulfate systems
Blend and Mixing Tanks
- Capacities from 300 to 6,500 gallons
Homogenizers
- For dispersing high-melting polymers into aqueous systems
- Emulsion refinement via particle size reduction
Dispersers
Effective dispersion of solids into aqueous systems
Pilot Production Capabilities
We offer a range of pilot-scale reactors (5 to 100 gallons) to support R&D and initial production trials, including:
- Stainless steel and glass reactors
- Steam, pressure, and hot-oil systems
- Reflux, distillation, straight & packed columns
- Organic synthesis and reaction testing
Organic Synthesis & Reaction Capabilities
Piedmont specializes in custom organic synthesis, designed to support complex product development and rapid commercialization. We tailor each synthesis program to customer needs and equipment compatibility.
Common Reaction Types:
- Acrylation, Alkylation, Amidation, Benzylation
- Carbamation, Carboxylation, Esterification
- Methylolation, Oxidation, Phosphation, Phosphonation
- Polymerization, Quaternization
- Saponification, Sulfation, Sulfonation
- Transamination, Transesterification
Product Realization: From Concept to Commercial Scale
Our custom chemical toll manufacturing services are built around the full lifecycle of product development. We provide:
- Safety and regulatory compliance reviews
- Molecular and formulation design
- Lab synthesis and application testing
- Pilot plant development and verification
- Full-scale production, scale-up, and delivery
This integrated process reduces time to market and ensures high-quality outcomes at every stage.
Why Choose Piedmont?
- Multi-site production in the Southeast US
- Custom chemical toll manufacturing leadership
- Experienced technical staff and agile scale-up capability
- Trusted by partners across Canada, Mexico, Central America, and Asia
- Flexible support for both specialty and volume-based needs
- Family-owned, customer-driven culture with 85+ years of excellence
Start Your Next Project With Us
Looking for a responsive, technically capable partner for custom chemical toll manufacturing in the USA? Piedmont Chemical is ready to help you move from formulation to full-scale production — efficiently, safely, and on your terms.
Contact us today to explore how our capabilities can bring your chemistry to life.